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Eye Registry

Health Research CEA Discovered CEA FAQ CHIC Eye Registry Health Archives

Eye Registry Release & Listing for PRA & CEA

The information found in the Eye Registry table represents the Toller DNA PRA Pattern A or Normal results received from OptiGen and individual test results submitted to NSDTRC (USA) Health & Genetics via the Listing Form. Toller participants from the original Baker Institute (BI) Study, who were instrumental in the development of the prcd-2 test, are indicated by * next to the Pattern letter.   Please use the Release & Listing Form to report all Optigen Pattern B (Carrier), C (Affected) and all Pattern BI Study results.

Effective after June 30, 2006, the Eye Registry will also report Toller DNA CEA Normal results received from OptiGen and individual test results submitted to NSDTRC (USA) Health & Genetics via the Release & Listing Form for Tollers tested as Carriers or Affecteds for CEA.

A copy of the "Listing Form" can be obtained by clicking the links below OR by contacting Laura Smith.

As with any database, errors may occur.  Please contact Laura Smith to correct any errors you find.

Eye Registry

  • PRA - CLICK HERE to download a copy of the NSDTRC (USA) Eye Registry-PRA in PDF format. Updated through 12/07.

  • CEA - CLICK HERE to download a copy of the NSDTRC (USA) Eye Registry-CEA in PDF format. Updated through 12/07.

Toller prcd-PRA Gene Discovered (06/01/2005)

OptiGen, LLC, proudly announces identification of the gene causing canine prcd-PRA (progressive rod-cone degeneration form of Progressive Retinal Atrophy). The cause of this inherited blinding disease, occurring in at least a dozen purebreds including the Nova Scotia Duck Tolling Retriever, is one specific mutation in the coding sequence of the gene. OptiGen now offers a direct gene mutation test to detect the prcd-PRA status of any dog among affected breeds.

The prcd-PRA mutation test can be obtained following the same procedures as before - see www.optigen.com. As of June 1, 2005, the fee for the prcd-PRA test is reduced 25%, down to $195. Opportunities for discounts for litters, through online ordering and 20/20 Clinics continue.

The Morris Animal Foundation/The Seeing Eye, Inc. is a major sponsor of this research by Drs. Acland and Aguirre. Grants from the NEI/NIH, the Foundation Fighting Blindness and The Van Sloan Fund with generous support from Neil and Sue Van Sloun and contributions from many breed clubs, organizations and individuals are gratefully acknowledged. Many club health committees and breeders gave welcome encouragement as well as invaluable samples and information on their breed lines.

We want to thank everyone who has participated in the PRA study through the years and those breeders who have used the marker test to reduce the incidence of the prcd-PRA disease in Tollers. We now have 100% confidence with this new gene mutation test.

CLICK HERE for the complete press release OR refer to the Optigen website at www.optigen.com

Questions? - Contact Jane Folkman

Jane Folkman, Health and Genetics Committee Chair
Sue Van Sloun, Health and Genetics Committee Co-Chair

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